A biomimetic, inexpensive and simple method for the stereoselective thio-Michael addition of thiols to chalcones has been developed using bovine serum albumin (BSA) as a catalyst. Optically active products are obtained in high yield and with enantiomeric excesses of up 70%
Stereoselective thio-Michael addition to chalcones in water catalyzed by bovine serum albumin / N. Gaggero, D. Albanese, G. Celentano, S. Banfi, A. Aresi. - In: TETRAHEDRON-ASYMMETRY. - ISSN 0957-4166. - 22:11(2011), pp. 1231-1233. [10.1016/j.tetasy.2011.06.024]
Stereoselective thio-Michael addition to chalcones in water catalyzed by bovine serum albumin
N. GaggeroPrimo
;D. AlbaneseSecondo
;G. CelentanoUltimo
;
2011
Abstract
A biomimetic, inexpensive and simple method for the stereoselective thio-Michael addition of thiols to chalcones has been developed using bovine serum albumin (BSA) as a catalyst. Optically active products are obtained in high yield and with enantiomeric excesses of up 70%
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