In order to determine whether gravity influences the growth of terrestrial mammals, systolic blood pressure, heart rate, urinary output and body weight were measured at 10-day intervals from the age of 30 days (weaning) to 150 days in 12 male Sprague-Dawley rats. Six rats were grown in a gravitational environment. 'Dry' water immersion was used to subject six rats to a microgravitational environment between the ages of 30 and 90 days. A downward shift in systolic blood pressure and body weight maturation curves was observed in the microgravitational group from the age of 60 days. After the 'dry' water immersion was stopped, the fully developed rats showed a significant increase in systolic blood pressure, which returned to control values, but not in body weight. We conclude that the physiological increase in systolic blood pressure taking place in rats during growth is partly dependent on gravity.
The effects of a microgravitational environment on the blood pressure maturation curve in normotensive rats / F. Magrini, M. Ciulla, R. Meazza, P. Reggiani. - In: JOURNAL OF HYPERTENSION SUPPLEMENT. - ISSN 0952-1178. - 7:6(1989 Dec), pp. S74-5-S75.
The effects of a microgravitational environment on the blood pressure maturation curve in normotensive rats
F. MagriniPrimo
;M. CiullaSecondo
;
1989
Abstract
In order to determine whether gravity influences the growth of terrestrial mammals, systolic blood pressure, heart rate, urinary output and body weight were measured at 10-day intervals from the age of 30 days (weaning) to 150 days in 12 male Sprague-Dawley rats. Six rats were grown in a gravitational environment. 'Dry' water immersion was used to subject six rats to a microgravitational environment between the ages of 30 and 90 days. A downward shift in systolic blood pressure and body weight maturation curves was observed in the microgravitational group from the age of 60 days. After the 'dry' water immersion was stopped, the fully developed rats showed a significant increase in systolic blood pressure, which returned to control values, but not in body weight. We conclude that the physiological increase in systolic blood pressure taking place in rats during growth is partly dependent on gravity.Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.