Neutrophils constitute the first line of defense against invading pathogens, but they also are responsible for tissue destruction in pathological conditions. In a recent paper published in Science Signaling, Junger and colleagues show that adenosine 5'-triphosphate release and signaling through purinergic P2 receptors upon neutrophil activation by bacterial and inflammatory stimuli represents an important mechanism for effective neutrophil functional response and host protection.
Purinergic control of neutrophil activation / F.M. Grassi. - In: JOURNAL OF MOLECULAR CELL BIOLOGY. - ISSN 1674-2788. - 2:4(2010), pp. 176-177. [10.1093/jmcb/mjq014]
Purinergic control of neutrophil activation
F.M. GrassiPrimo
2010
Abstract
Neutrophils constitute the first line of defense against invading pathogens, but they also are responsible for tissue destruction in pathological conditions. In a recent paper published in Science Signaling, Junger and colleagues show that adenosine 5'-triphosphate release and signaling through purinergic P2 receptors upon neutrophil activation by bacterial and inflammatory stimuli represents an important mechanism for effective neutrophil functional response and host protection.Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.