The enantioselective synthesis of the lupinine alkaloid (+)-aloperine is described. The synthetic scheme presents three steps that are mediated by enzymes: kinetic resolution, oxidation of a primary alcohol to an aldehyde and oxidation of a secondary alcohol to a ketone.
Enzymes assisted enantioselective synthesis of the alkaloid (+)-Aloperine / A. Barilli, F. Belinghieri, D. Passarella, G. Lesma, S. Riva, A. Silvani, B. Danieli. - In: TETRAHEDRON-ASYMMETRY. - ISSN 0957-4166. - 15:18(2004), pp. 2921-2925. [10.1016/j.tetasy.2004.06.056]
Enzymes assisted enantioselective synthesis of the alkaloid (+)-Aloperine
D. Passarella;G. Lesma;A. Silvani;B. Danieli
2004
Abstract
The enantioselective synthesis of the lupinine alkaloid (+)-aloperine is described. The synthetic scheme presents three steps that are mediated by enzymes: kinetic resolution, oxidation of a primary alcohol to an aldehyde and oxidation of a secondary alcohol to a ketone.File in questo prodotto:
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