The present invention relates to the use of inhibitors of the histone deacetylases for the preparation of a medicament for the treatment of pathologies caused by increased levels of plasma cholesterol and plasma and hepatic triglycerides. Particularly, the invention relates to the use of said inhibitors for the preparation of a medicament for the treatment of diseases such as hyperlipidaemia, particularly, hypercholesterolaemia, hypertriglyceridaemia, atherosclerosis, cardiovascular and cerebrovascular pathologies, obesity, diabetes metabolic syndromes.

Inhibition of histone deacetylases for the treatment of hyperlipidemias and prevention of atherosclerosis and cardiovascular diseases / M. Crestani, C. Godio, N. Mitro.

Inhibition of histone deacetylases for the treatment of hyperlipidemias and prevention of atherosclerosis and cardiovascular diseases

M. Crestani
Primo
;
C. Godio
Secondo
;
N. Mitro
Ultimo
2005

Abstract

The present invention relates to the use of inhibitors of the histone deacetylases for the preparation of a medicament for the treatment of pathologies caused by increased levels of plasma cholesterol and plasma and hepatic triglycerides. Particularly, the invention relates to the use of said inhibitors for the preparation of a medicament for the treatment of diseases such as hyperlipidaemia, particularly, hypercholesterolaemia, hypertriglyceridaemia, atherosclerosis, cardiovascular and cerebrovascular pathologies, obesity, diabetes metabolic syndromes.
Università degli Studi di Milano
WO2005/105066
PCT/IT2005/000248
10-nov-2005
histone deacetylase inhibitor; hyperlipidemia treatment; atherosclerosis prevention; cardiovascular disease prevention
Settore BIO/10 - Biochimica
http://sobjprd.questel.fr/sobj/servlet/get_pds/WO2005105066A2.pdf?userid=qptui001&type=0&pdfid=5906911&ekey=926&id=-56481859
Inhibition of histone deacetylases for the treatment of hyperlipidemias and prevention of atherosclerosis and cardiovascular diseases / M. Crestani, C. Godio, N. Mitro.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/12398
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